Reproductive and obstetrical outcomes with the overall survival of fertile-age women treated with fertility-sparing surgery for borderline ovarian tumors in Sweden: a prospective nationwide population-based study

ObjectiveTo assess the efficacy of fertility-sparing surgery (FSS) in terms reproductive outcomes by following FSS for borderline ovarian tumors (BOTs) and comparing safety versus radical (RS).DesignNationwide cohort study based on prospectively recorded data.SettingSweden.Patient (s)All women age (18–40 years) treated Sweden stage I BOT with use or RS from 2008 to 2015, identified Swedish Quality Registry Gynecologic Cancer (SQRGC).Interventions (s)FSS RS.Main Outcome Measure (s)Reproductive outcomes: natural conception, assisted technology (ART), live birth obstetrical outcomes. Safety outcome: overall survival (OS) rates, undergoing RS. The was linked Medical Birth Register identify all who had given after obtain detailed data. For information ART treatment, National Assisted Reproduction consulted. OS rate comparisons were conducted means Kaplan-Meier estimates.Result (s)Of 277 BOTs, 213 (77%) underwent FSS, 183 (86%) unilateral salpingo-oophorectomy, 30 (14%) cystectomy. Following 50 gave 62 healthy children, 8% which preterm. Only 20 (9%) treatment. similar RS.Conclusion (s)Natural fertility maintained FSS; only 9% required also deemed be equivalent regarding outcome. To (RS). Nationwide Sweden. All (SQRGC). Reproductive estimates. Of Natural